Our synthetic chemistry teams have many years of combined experience in chemical route design, organic synthesis and purification. We can conduct fee for service projects to deliver milligrams to hundreds of grams.

In addition to common reactions, Hande’s chemistry teams have substantial experience with:

  • Fluorination, oxidation, ozonolysis, diazotization and nitration (in batch mode or using flow chemistry) reactions.

  • Hydrogenations (including asymmetric) and hydrogenolysis, and reductions (using LiAlH4, NaBH4, Red-Al etc.).

  • Pd, Pt, Rh, Ru, Ir-catalyzed reactions (including, Ullmann, Buchwald-Hartwig, Suzuki, Heck, Negishi, carbonylations, olefin metathesis etc.).

  • Cryogenic reactions, including organometallic reactions (n-BuLi, MeLi, Grignard reagents etc.).

  • Asymmetric synthesis.

  • Enzyme-catalyzed resolution, chemical resolution.

  • Please feel free to contact us if you have any questions.